From a tiny sample of tissue no larger than a grain of sand, scientists have come within reach of a goal once thought unattainable: building a complete functional wiring diagram of a portion of the brain. In 1979, famed molecular biologist,…
Category: 5. Health
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Treatment for mitochondrial diseases within reach
A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic defects disrupt cellular energy production. Researchers at the University of Gothenburg have identified a molecule that helps more…
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By re-creating neural pathway in dish, Stanford Medicine research may speed pain treatment
Stanford Medicine investigators have replicated, in a lab dish, one of humans’ most prominent nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the brain. Once further processed in the brain, these…
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A comprehensive map of the human cell
Scientists have attempted to map the human cell since the first microscope was invented more than 400 years ago. But many components of the cell still remain uncharted.
“We know each of the proteins that exist in our cells, but how they fit…
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Osteoarthritis: Largest genome-wide association study uncovers drug targets and therapy opportunities
Osteoarthritis is the leading cause of disability and chronic pain worldwide, affecting an estimated 595 million people globally. Projections suggest that this number will rise to 1 billion by 2050. Despite its profound impact on individuals and…
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Researchers identify growing list of genetic disorders treatable before or immediately after birth
Researchers from Mass General Brigham, Harvard Medical School and Duke University School of Medicine have identified nearly 300 genetic disorders that can be treated before or immediately after a baby is born. This “treatable fetal findings list”…
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New gene editing tool shows promise for treating diseases with multiple mutations
Investigators from Mass General Brigham and Beth Israel Deaconess Medical Center have developed STITCHR, a new gene editing tool that can insert therapeutic genes into specific locations without causing unwanted mutations. The system can be…
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Your skin is breathing: New wearable device can measure it
Northwestern University researchers have developed the first wearable device for measuring gases emitted from and absorbed by the skin.
By analyzing these gases, the device offers an entirely new way to assess skin health, including monitoring…
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Engineering smart delivery for gene editors
Modern genome editing techniques, including CRISPR systems, hold great potential for treating genetic diseases. However, delivering these molecular tools reliably to their target cells remains a significant challenge.
“Previous viral and…
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‘Sugar’ signatures help identify and classify pancreatic cancer cell subtypes
Van Andel Institute scientists and collaborators have developed a new method for identifying and classifying pancreatic cancer cell subtypes based on sugars found on the outside of cancer cells.
These sugars, called glycans, help cells recognize…
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